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中文名稱：大鼠血管緊張素Ⅱ(ANG-Ⅱ)酶聯免疫試劑盒
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貨號：CSB-E04494r
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規格：96T/48T
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價格：￥3900/￥2500
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其他：
產品詳情
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產品描述：大鼠血管緊張素Ⅱ(ANG-Ⅱ)酶聯免疫試劑盒（CSB-E04494r）為競爭法ELISA試劑盒，定量檢測血清、血漿.樣本中的ANG-Ⅱ含量。ANG-Ⅱ是重要的靶點。它是腎素-血管緊張素系統的關鍵效應肽。其作用機制主要是通過與受體結合，收縮血管、促進醛固酮分泌，影響血壓調節、水鹽平衡等。對它的研究有助于深入了解心血管疾病等病理生理過程，為相關治療提供方向。試劑盒檢測范圍為15.6 pg/ml-1000 pg/ml.，該產品適用于基礎科研場景，如心血管疾病動物模型研究、藥物干預對血管活性物質的影響評估，或腎臟功能與體液平衡相關機制探索，為實驗室提供穩定可靠的檢測工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：angiotensin II,ANG-Ⅱ,angiotensin 2,ANG-2
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縮寫：ANG-Ⅱ
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種屬：Rattus norvegicus (Rat)
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樣本類型：serum, plasma.
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檢測范圍：15.6 pg/ml-1000 pg/ml.
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靈敏度：7.8 pg/ml.
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Cardiovascular
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<12%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of rat ANG-Ⅱ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
Sample
Serum(n=4)
1:1
Average %
84
Range %
80-92
1:2
Average %
87
Range %
81-95
1:4
Average %
90
Range %
92-97
1:8
Average %
93
Range %
86-98
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回收率：
The recovery of rat ANG-Ⅱ spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample Type
Average % Recovery
Range
Serum (n=5)
92
86-98
EDTA plasma (n=4)
87
82-95
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標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
pg/ml
OD1
OD2
Average
1000
0.158
0.160
0.159
500
0.185
0.189
0.187
250
0.237
0.232
0.235
125
0.364
0.340
0.352
62.5
0.595
0.568
0.581
31.25
0.958
0.902
0.930
15.6
1.355
1.298
1.326
0
2.287
2.126
2.206
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數據處理：
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貨期：3-5 working days
引用文獻
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靶點詳情
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最新研究進展：ANG-Ⅱ是一種細胞因子，在機體內具有廣泛的生物學功能，包括調節血壓、腎功能和心血管系統等。近年來的研究發現，ANG-Ⅱ還具有免疫調節作用，能夠通過調節細胞凋亡、自噬、炎癥反應等多種機制調節機體的免疫反應。
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