Rat Alpha-1-antitrypsin(SERPINA1) ELISA kit
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中文名稱:大鼠α1-抗胰蛋白酶(SERPINA1)酶聯免疫試劑盒
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貨號:CSB-EL021053RA
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規格:96T/48T
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價格:¥3600/¥2500
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其他:
產品詳情
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產品描述:大鼠α1-抗胰蛋白酶(SERPINA1)酶聯免疫試劑盒(CSB-EL021053RA)為競爭法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的SERPINA1含量。SERPINA1是重要靶點,其編碼的α1 - 抗胰蛋白酶可抑制多種蛋白酶活性。研究發現它與肺部疾病、肝臟疾病等密切相關,機制可能是其異常導致蛋白酶 - 抗蛋白酶失衡,引發組織損傷,目前圍繞它的治療研究在積極開展。試劑盒檢測范圍為62.5 ng/mL-4000 ng/mL,適用于科研領域中對肝臟功能、炎癥反應或代謝異常相關機制的研究,例如肝損傷模型評估、蛋白酶 - 抗蛋白酶系統平衡分析,以及藥物干預實驗中的生物標志物檢測,為相關基礎研究和生物醫學探索提供可靠工具。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:Serpina1Alpha-1-antiproteinase ELISA kit; Alpha-1-antitrypsin ELISA kit; Alpha-1-proteinase inhibitor ELISA kit; Serpin A1 ELISA kit
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縮寫:
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Uniprot No.:
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種屬:Rattus norvegicus (Rat)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:62.5 ng/mL-4000 ng/mL
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靈敏度:15.6 ng/mL
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Cardiovascular
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測定原理:quantitative
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測定方法:Competitive
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數據處理:
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貨期:3-5 working days
相關產品
靶點詳情
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功能:Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.
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基因功能參考文獻:
- A1AT bidirectional uptake and secretion from lung endothelial cells towards the alveolar epithelium and airspaces PMID: 24743137
- These results suggest that transfer of the N-terminal acidic extension of HCII to alpha1-PI M358R enhanced its inhibition of thrombin by conferring the ability to bind exosite 1 on HAPI M358R. PMID: 16981704
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亞細胞定位:Secreted.
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蛋白家族:Serpin family
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組織特異性:Plasma.
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數據庫鏈接:
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