Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

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中文名稱：

小鼠Ⅰ型膠原C端肽(CTX-Ⅰ)酶聯免疫試劑盒
貨號：

CSB-E12782m
規格：

96T/48T
價格：

￥3600/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產品描述：

小鼠Ⅰ型膠原C端肽(CTX-Ⅰ)酶聯免疫試劑盒（CSB-E12782m）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿.樣本中的CTX-Ⅰ含量。CTX-Ⅰ，即Ⅰ型膠原C端肽，是膠原蛋白分解代謝的關鍵產物，其濃度變化反映骨基質降解活性，常用于骨代謝異常、骨質疏松模型研究及骨相關疾病的機制探索。研究機制涉及CTX-Ⅰ在骨吸收過程中的生成和作用，以及與骨代謝相關疾病的關系。試劑盒檢測范圍為0.23 ng/ml-15 ng/ml.，CTX - Ⅰ是Ⅰ型膠原蛋白分解代謝的關鍵產物，其濃度變化可反映骨基質降解活性，常用于骨代謝異常、骨質疏松模型研究及骨相關疾病的機制探索?？蒲袌鼍爸锌捎糜谠u估骨吸收標志物水平，例如在骨質疏松動物模型中動態監測骨質流失程度，或結合藥物干預實驗探究骨代謝調控機制。支持科研人員高效完成骨代謝相關的基礎研究與藥效評價。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

cross linked C-telopeptide of type 1 collagen (CTX-1),_x000D_cross linked C-telopeptide of type I collagen (CTX-I)
縮寫：

CTX-Ⅰ
種屬：

Mus musculus (Mouse)
樣本類型：

serum, plasma, tissue homogenates.
檢測范圍：

0.23 ng/ml-15 ng/ml.
靈敏度：

0.12 ng/ml.
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Others
測定原理：

quantitative
測定方法：

Competitive

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of mouse CTX-Ⅰ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:1	Average %	84
	Range %	80-92
1:2	Average %	87
	Range %	81-94
1:4	Average %	88
	Range %	82-95
1:8	Average %	93
	Range %	86-98

回收率：

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml

OD1

OD2

Average

0.195

0.204

0.200

7.5

0.246

0.260

0.253

3.75

0.339

0.348

0.344

1.87

0.518

0.529

0.524

0.94

0.851

0.841

0.846

0.47

1.272

1.253

1.262

0.23

1.838

1.784

1.811

2.512

2.525

2.518

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

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最新研究進展：

Ⅰ型膠原交聯脫氨酸肽（CTX-Ⅰ）是膠原蛋白分解產物之一，它被認為是骨吸收的生物標志物之一。CTX-Ⅰ的檢測可以用于評估骨吸收水平，是一種廣泛應用的臨床診斷指標。最近的研究表明，CTX-Ⅰ還與一些非骨代謝方面的疾病有關，例如心血管疾病、糖尿病、腎臟疾病等。

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.