Human Group IIF secretory phospholipase A2(PLA2G2F) ELISA kit
-
中文名稱：人IIF組分泌型磷脂酶A2(PLA2G2F)酶聯(lián)免疫試劑盒
-
貨號(hào)：CSB-EL018095HU
-
規(guī)格：96T/48T
-
價(jià)格：￥3600/￥2500
-
其他：
產(chǎn)品詳情
-
產(chǎn)品描述：人IIF組分泌型磷脂酶A2(PLA2G2F)酶聯(lián)免疫試劑盒（CSB-EL018095HU）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、tissue,勻漿樣本中的PLA2G2F含量。PLA2G2F，即磷脂酶A2家族IIF分泌型磷脂酶，是一種鈣依賴性磷脂酶，主要靶向細(xì)胞外磷脂。其通過(guò)水解磷脂中的酯鍵釋放脂肪酸，參與炎癥條件下脂質(zhì)介質(zhì)的產(chǎn)生。PLA2G2F在炎癥、免疫和代謝等多種生理過(guò)程中發(fā)揮重要作用。試劑盒檢測(cè)范圍為0.312 ng/mL-20 ng/mL，本試劑盒適用于探索其在動(dòng)脈粥樣硬化、代謝紊亂等病理過(guò)程中的作用機(jī)制研究，或評(píng)估疾病模型中酶活性變化等科研用途。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書。
-
別名：PLA2G2FGroup IIF secretory phospholipase A2 ELISA Kit; GIIF sPLA2 ELISA Kit; sPLA2-IIF ELISA Kit; EC 3.1.1.4 ELISA Kit; Phosphatidylcholine 2-acylhydrolase 2F ELISA Kit
-
縮寫：
-
Uniprot No.：
-
種屬：Homo sapiens (Human)
-
樣本類型：serum, plasma, tissue,homogenates
-
檢測(cè)范圍：0.312 ng/mL-20 ng/mL
-
靈敏度：0.078 ng/mL
-
反應(yīng)時(shí)間：1-5h
-
樣本體積：50-100ul
-
檢測(cè)波長(zhǎng)：450 nm
-
研究領(lǐng)域：Metabolism
-
測(cè)定原理：quantitative
-
測(cè)定方法：Sandwich
-
數(shù)據(jù)處理：
-
貨期：3-5 working days
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids (phospholipase A2 activity), the catalytic efficiency decreasing in the following order: phosphatidylglycerols > phosphatidylethanolamines > phosphatidylcholines > phosphatidylserines. May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases.
-
基因功能參考文獻(xiàn)：
- two of these isoforms, sPLA2 IIA and sPLA2 IIF, localize to the upper stratum granulosum and increase in response to experimental barrier perturbation. PMID: 24269828
-
亞細(xì)胞定位：[Isoform 1]: Secreted. Cell membrane; Peripheral membrane protein.
-
蛋白家族：Phospholipase A2 family
-
組織特異性：Expressed at high levels in placenta, testis, thymus and at lower levels in heart, kidney, liver and prostate. Highly expressed in rheumatoid arthritic tissues, including synovial lining cells in the intima, capillary endothelial cells and plasma cells.
-
數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-
