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中文名稱：人花生四烯酸(AA)酶聯免疫試劑盒
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貨號：CSB-E09040h
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規格：96T/48T
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價格：￥3600/￥2500
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其他：
產品詳情
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產品描述：人花生四烯酸(AA)酶聯免疫試劑盒（CSB-E09040h）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織培養上清液、組織勻漿樣本中的AA含量。花生四烯酸（AA）是一種必需脂肪酸，其代謝產物在炎癥、免疫和神經系統功能中起關鍵作用。AA通過環氧化酶（COX）和脂氧合酶（LOX）途徑轉化為前列腺素和白三烯等生物活性分子，這些分子在多種疾病如癌癥、炎癥和心血管疾病中扮演重要角色。研究AA的代謝途徑和靶點對于開發治療這些疾病的新療法具有重要意義。試劑盒檢測范圍為78.125 ng/mL-5000 ng/mL，靈敏度為69.748 ng/mL。適用于基礎科研中炎癥機制研究、脂質代謝調控實驗、藥物或營養干預對AA通路影響的評估，以及細胞模型中AA釋放水平的動態監測。該檢測體系可為探索AA在心血管疾病、神經退行性疾病等病理生理過程中的作用提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：N/A
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縮寫：AA
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma, cell culture supernates, tissue homogenates
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檢測范圍：78.125 ng/mL-5000 ng/mL
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靈敏度：69.748 ng/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Biochemicals
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human AA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數據處理：
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貨期：3-5 working days
引用文獻
- Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma X Zhang,Cancer communications,2023
- Aqueous Extract of Tournefortia sarmentosa Stem Inhibits ADP-induced Platelet Aggregation Wang, L.et al, Indian Journal of Pharmaceutical Sciences ,2017
- Inhibitory Effects of Total Saponin Korean Red Ginseng on Thromboxane A Jung-Hae Shin.et al, The Korean Society For Biomedical Laboratory Sciences,2017
- Inhibitory effects of thromboxane A2 generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A2 phosphorylation Jung-Hae Shin.et al,Journal of Ginseng Research,2018
- Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production Lee S.et al,Cell Physiol Biochem,2017
- Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y1 and P2Y12 Receptors Chang-Chieh Wu.et al,BioMed Research International,2016
- H-rev107 Regulates Cytochrome P450 Reductase Activity and Increases Lipid Accumulation Tsai FM. et al,PLoS One,2015
產品評價
相關產品
靶點詳情
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最新研究進展：近年來，花生四烯酸（Arachidonic Acid，AA）的研究重點主要集中在其與疾病的關系、作用機制以及調節方法等方面。一些研究表明，花生四烯酸的代謝異常與多種疾病密切相關。例如，心血管疾病的發生與發展與花生四烯酸的代謝異常有關，AA通過氧化代謝生成的炎癥介質，如前列腺素和白三烯等，可導致血管內皮損傷、炎癥反應和血栓形成等。同時，花生四烯酸在腫瘤發生和發展中也發揮了一定的作用。花生四烯酸代謝產物可以促進腫瘤細胞增殖、侵襲和轉移，并在腫瘤的血管生成過程中發揮一定的作用。研究人員可通過調節花生四烯酸的代謝途徑，探索其在疾病預防和治療方面的作用機制。例如，一些研究表明，通過調節花生四烯酸代謝途徑，可以降低炎癥介質的生成，從而減輕炎癥反應，預防和治療炎癥性疾病。此外，還有一些研究試圖通過抑制花生四烯酸代謝途徑，阻止腫瘤細胞的生長和擴散，具有一定的潛在治療價值。
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