GPM6B Antibody, Biotin conjugated
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中文名稱：GPM6B兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA614417LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) GPM6B Polyclonal antibody
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Uniprot No.：
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基因名：GPM6B
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別名：GPM6B; M6B; Neuronal membrane glycoprotein M6-b; M6b
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Neuronal membrane glycoprotein M6-b protein (1-64AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.
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基因功能參考文獻：
- Increase in the expression levels of mRNA and protein for the Gpm6B is associated with various types of gynaecological malignancy. PMID: 25113253
- Circulating levels of DR6 and Gpm6B correlate with breast cancer tumor grade. PMID: 24696529
- Data show the Differences in high resolution melting analysis in promoters of tumor markers neuronal membrane glycoprotein M6-B, melanoma antigen family A12 and immunoglobulin superfamily Fc receptor indicated invasiveness of hepatocellular carcinoma. PMID: 23950870
- Microarray expression analysis of GPM6B-depleted osteogenic human mesenchymal stem cells revealed significant changes in genes involved in cytoskeleton organization and biogenesis. PMID: 21638316
- it is unlikely that mutations in M6B have a role in Pelizaeus-Merzbacher-like syndrome, as examined in eight patients PMID: 15214007
- Data suggest that M6B regulates serotonin uptake by affecting cellular trafficking of the serotonin transporter. PMID: 18581270
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亞細胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Myelin proteolipid protein family
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組織特異性：Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.
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數據庫鏈接：
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